Meblanios is an Aztreonam and Avibactam injectable combination associated with the management of selected difficult-to-treat Gram-negative bacterial infections. Understanding Meblanios requires looking at its two components, Aztreonam and Avibactam, and how their complementary properties relate to bacterial resistance mechanisms such as metallo-beta-lactamases (MBLs). As antimicrobial resistance becomes increasingly complex, combinations designed around specific resistance mechanisms...Read More